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Title |
Sequence analysis of 16S rRNA gene in Rhinosporidium seeberi shows similarity to plant chloroplast DNA
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Authors |
Karvita B Ahluwalia1*, Dhara B Dhaulakhandi1, Lalit C Garg2
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Affiliation |
1Cell Biology and Electron Microscope Section, Department of Biophysics, All India Institute of Medical Sciences, New Delhi – 110029, India; 2Gene Regulation Laboratory, National Institute of Immunology, New Delhi – 110067, India;
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E-mail* |
karvitaa@yahoo.com; * Corresponding author
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Phone |
+911126535914
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Article Type |
Hypothesis
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Date |
Received June 28, 2010; Accepted August 26, 2010; Published September 20, 2010 |
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Abstract |
Identity of causative agent of rhinosporidiosis (Rhinosporidium seeberi ) has been controversial since the disease was described in 1900. Extensive sequence alignments and phylogenetic analyses of 16S rRNA gene detected recently by us in R. seeberi , revealed 99% similarity with 16S rDNA in chloroplasts of flowering plants. Study demonstrates R. seeberi is a pigmented prokaryote displaying some characteristics of cyanobacteria, and contains 16S rDNA present in chloroplasts of all groups of land plants. This study and our recent publication of 2006 are the first molecular studies using purified organismal DNA extracted from R. seeberi free of infected tissue. |
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Keywords |
Rhinosporidium seeberi ; 16S rRNA gene; sequence analysis; chloroplast DNA; molecular phylogeny. |
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Citation |
Ahluwalia et al. Bioinformation 5(3): 89-96 (2010) |
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Edited by |
P. Kangueane
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ISSN |
0973-2063
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Publisher |
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License |
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License. |