BACK TO CONTENTS   |    PDF   |    PREVIOUS   |    NEXT

Title

 

 

 

 

 

Integrating T-cell epitope annotations with sequence and structural information using DAS

 

Authors

 

 Carmen M. Díez-Rivero1, María García-Boronat1 and Pedro A Reche1, *

 

Affiliation

 

 

1ImmuneMedicine Group, Department of Microbiology, Division of Immunology, Facultad de Medicina, Universidad Complutense de Madrid, Ave Complutense, s/n. Madrid 28040, Spain

 

Email

 

 parecheg@med.ucm.es

Phone

34 91 394 7229

Fax

 34 91 394 1641; *Corresponding author

Article Type

 

Database

Date

 

received November 09, 2008; accepted November 23, 2008; published December 06, 2008

Abstract

Immunoinformatics is an emerging new field that benefits from computational analyses and tools that facilitate the understanding of the immune system. A large number of immunoinformatics resources such as immune-related databases and analysis software are available through the World Wide Web for the benefit of the research community. However, immunoinformatics developments have sometimes remained isolated from mainstream bioinformatics. Therefore, there is clearly a need for integration, which will empower the exchange of data and annotations within the scientific community in a quick and efficient fashion. Here, we have chosen the Distributed Annotation System (DAS), for integrating in house annotations on experimental and predicted HLA I-restriction elements of CD8 T-cell epitopes with sequence and structural information.

 

Keywords

 DAS; annotation; epitope; HLA I

Citation

 

 Díez-Rivero et al., Bioinformation 3(4): 156-158 (2008)

 

Edited by

 

P. Kangueane

 

ISSN

 

0973-2063

 

Publisher

 

Biomedical Informatics

License

 

 

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.