Title
|
|
Integrating T-cell epitope annotations with sequence and structural information using DAS
|
Authors
|
Carmen M. Díez-Rivero1, María García-Boronat1 and Pedro A Reche1, *
| |
Affiliation
|
1ImmuneMedicine Group, Department of Microbiology, Division of Immunology, Facultad de Medicina, Universidad Complutense de Madrid, Ave Complutense, s/n. Madrid 28040, Spain
| |
|
||
Phone |
34 91 394 7229 | |
Fax |
34 91 394 1641; *Corresponding author | |
Article Type
|
Database | |
Date
|
received November 09, 2008; accepted November 23, 2008; published December 06, 2008 | |
Abstract |
Immunoinformatics is an emerging new field that benefits from computational analyses and tools that facilitate the understanding of the immune system. A large number of immunoinformatics resources such as immune-related databases and analysis software are available through the World Wide Web for the benefit of the research community. However, immunoinformatics developments have sometimes remained isolated from mainstream bioinformatics. Therefore, there is clearly a need for integration, which will empower the exchange of data and annotations within the scientific community in a quick and efficient fashion. Here, we have chosen the Distributed Annotation System (DAS), for integrating in house annotations on experimental and predicted HLA I-restriction elements of CD8 T-cell epitopes with sequence and structural information.
| |
Keywords |
DAS; annotation; epitope; HLA I | |
Citation
|
Díez-Rivero et al., Bioinformation 3(4): 156-158 (2008)
| |
Edited by
|
P. Kangueane
| |
ISSN
|
0973-2063
| |
Publisher
|
Biomedical Informatics | |
License
|
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
|