Title

SNP-Flankplus: SNP ID-centric retrieval for SNP flanking sequences

Authors

 Cheng-Hong Yang¹, Yu-Huei Cheng¹, Li-Yeh Chuang² and Hsueh-Wei Chang^{3, 4, 5,} *

Affiliation

¹Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Taiwan; ²Department of Chemical Engineering, I-Shou University, Taiwan; ³Faculty of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Taiwan; ⁴Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Taiwan; ⁵Center of Excellence for Environmental Medicine, Kaohsiung Medical University, Taiwan;

Email

changhw@kmu.edu.tw; *Corresponding author

Article Type

Web Server

Date

received November 25, 2008; accepted December 01, 2008; published December 06, 2008

Abstract

The flanking sequences provided by dbSNP of NCBI are usually short and fixed length without further extension, thus making the design of appropriate PCR primers difficult. Here, we introduce a tool named “SNP-Flankplus” to provide a web environment for retrieval of SNP flanking sequences from both the dbSNP and the nucleotide databases of NCBI. Two SNP ID types, rs# and ss#, are acceptable for querying SNP flanking sequences with adjustable lengths for at least sixteen organisms.

Keywords

PCR; SNP; primer design; flanking sequences

Citation

Yang et al., Bioinformation 3(4): 147-149 (2008)

Edited by

P. Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.