Title

ESBRI: A web server for evaluating salt bridges in proteins

Authors

Susan Costantini^{1, 2, 3}, Giovanni Colonna², and Angelo M. Facchiano^{1, 2,} *

Affiliation

¹Laboratory of Bioinformatics and Computational Biology, Institute of Food Science, CNR, via Roma 52 A/C, 83100 Avellino, Italy; ²CRISCEB, Research Center of Computational and Biotechnological Sciences, Second University of Naples, via Costantinopoli 16, 80138 Naples, Italy; ³CROM, Oncology Research Center of Mercogliano, “Fiorentino Lo Vuolo”, via Ammiraglio Bianco, 83013 Mercogliano, Italy

Email

angelo.facchiano@isa.cnr.it; Corresponding author

39 0825 299625

39 0825 299813

Article Type

Prediction Model

Date

received September 16, 2008; revised October 10; accepted October 15, 2008; published November 09, 2008

Abstract

Salt bridges can play important roles in protein structure and function and have stabilizing and destabilizing effects in protein folding. ESBRI is a software available as web tool which analyses the salt bridges in a protein structure, starting from the atomic coordinates. In the case of protein complexes, the salt bridges between protein chains can be evaluated, as well as those among specific charged amino acids and the different protein subunits, in order to obtain useful information regard the protein-protein interaction.

Keywords

salt bridges; peptides; proteins; protein-protein interaction; web-software

Citation

Costantini et al. Bioinformation 3(2): 137-138  (2008)

Edited by

P. Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.