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Title
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Mitochondrial gene rearrangements: new paradigm in the evolutionary biology and systematics
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Authors
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Tiratha Raj Singh
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Affiliation
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Department of Bioinformatics, Maulana Azad National Institute of Technology (MANIT), Bhopal, India. *Department of Zoology, Faculty of Life Sciences, Tel-Aviv University, Tel-Aviv, Israel *Present address
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Article Type
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Current Trends
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Date
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received August 10, 2008; revised September 27 2008; accepted September 30, 2008; published October 25, 2008 | |
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Abstract |
Mitochondrial (mt) genomic study may reveal significant insight into the molecular evolution and several other aspects of genome evolution such as gene rearrangements evolution, gene regulation, and replication mechanisms. Other questions such as patterns of gene expression mechanism evolution, genomic variation and its correlation with physiology, and other molecular and biochemical mechanisms can be addressed by the mt genomics. Rare genomic changes have attracted evolutionary biology community for providing homoplasy free evidence of phylogenetic relationships. Gene rearrangements are considered to be rare evolutionary events and are being used to reconstruct the phylogeny of diverse group of organisms. Mt gene rearrangements have been established as a hotspot for the phylogenetic and evolutionary analysis of closely as well as distantly related organisms.
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Keywords
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gene expression; evolution; mitochondrial gene; genomic variation; replication; gene regulation
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Citation
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Singh et al., Bioinformation 3(1): 95-97 (2008)
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Edited by
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P. Kangueane
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ISSN
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0973-2063
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Publisher
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Biomedical Informatics
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License
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This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
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