Title

Database of neurodegenerative disorders

Authors

Ragul Gowthaman^{1, *}, Nithiyadevi Gowthaman¹, Madhan Kumar Rajangam¹ and Kalyanaraman Srinivasan²

Affiliation

¹Department of Bioinformatics, School of Chemical & Biotechnology, SASTRA University, Thanjavur-613402, India; ²Department of computer science, National Institute of Technology, Trichy-620015, India

Email

g.ragul@gmail.com; * Corresponding author

Article Type

Web Database

Date

received November 13, 2007; revised December 03, 2007; accepted December 05, 2007; published online December 11, 2007

A neurological disorder is a disorder caused by the deterioration of certain nerve cells called neurons. Changes in these cells cause them to function abnormally, eventually bringing about their death. In this paper we present a comprehensive database for neurodegenerative diseases, a first-of-its kind covering all known or suspected genes, proteins, pathways related to neurodegenerative diseases. This dynamically compiled database allows researchers to link neurological disorders to the candidate genes & proteins. It serves as a tool to navigate potential gene-protein-pathway relationships in the context of neurodegenerative diseases. The neurodegenerative disorder database covers more then 100 disease concepts including synonyms and research topics. The current version of the database provides links to 728 abstracts and over 203 unique genes/proteins with 137 drugs. Also it is integrated well with other related databases. The aim of this database is to provide the researcher with a quick overview of potential links between genes and proteins with related neurodegenerative diseases. Thus DND providing a user-friendly interface is designed as a source to enhance research on neurodegenerative disorders.

http://www.bioinfosastra.com/services/dnd/dnd.html

neurodegenerative disorder; neurological disorders; web database

Citation

Gowthaman, et al., Bioinformation 2(4): 153-154 (2007)

Edited by

P. Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.