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Title

MAP MUTATION: a program for analyzing mutations in protein sequences

 

Authors

Tamanna Anwar 1 and Asad U Khan 1,2*

 

Affiliation

1Distribution Information Sub Centre, 2Interdisciplinary Biotechnology Unit Aligarh Muslim University, Aligarh 202002 India.

 

E-mail*

huzzi99@hotmail.com; * Corresponding author

 

Phone

 

091-571-2723088

 

Fax

 

091-571-2721776

 

Article Type

 

Software

 

Date

 

received February 08 2006; accepted February 12 2006; published online February 20, 2006

 

Abstract

 

Avian influenza is an infectious disease of birds caused by type-A strains of the influenza virus. The unprecedented spread of the highly pathogenic avian influenza type A is a threat to veterinary and human health. Influenza viruses continuously undergo mutations and they lack proofreading mechanism. Hence, they evolve to new forms of the virus. We describe MAP MUTATION (developed using PERL script) to quickly compare two strains and display mutational information and report specific positions where mutation has occurred.

 

Availability

 

The PERL script is available from the authors for non-commercial purposes.

 

Keywords

 

sequence; mutation; virus; PERL script; analysis

 

Citation

 

Anwar & Khan, Bioinformation 1(3): 92-93 (2006)

 

Edited by

 

P. Kangueane

 

ISSN

 

0973-2063

 

Publisher

 

Biomedical Informatics

 

License

 

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.