Title

Molecular docking analysis of Aza compounds with the heme-binding protein from Tannerella Forsythia

Authors

Janani Sathiamurthy¹, Gayathri Rengasamy*¹, Surya Sekaran², Kavitha Sankaran¹, Vishnu Priya Veeraraghavan¹ & Rajalakshmanan Eswaramoorthy*²

Affiliation

¹Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai-600077; ²Department of Biomaterials (Green lab), Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai-600077 ; *Corresponding author

Email

Janani Sathiamurthy – E-mail: sathiamurthyganapathydr@gmail.com

Gayathri Rengasamy - E-mail: gayathri.sdc@saveetha.com

Surya Sekaran - E-mail: suryas.sdc@saveetha.com

Vishnu Priya Veeraraghavan - E-mail: vishnupriya@saveetha.com

Kavitha Sankaran - E-mail: kavithas.sdc@saveetha.com

Rajalakshmanan Eswaramoorthy - E-mail: rajalakshmanane.sdc@saveetha.com

Article Type

Research Article

Date

Received January 1, 2023; Revised January 30, 2023; Accepted January 31, 2023, Published January 31, 2023

The high biological activity and interesting optical properties of the aza compounds is known. Therefore, it is of interest to document the molecular docking analysis data of Aza compounds with the heme-binding protein from an anaerobic, Gram-negative bacterium Tannerella Forsythia. Hence, we report the optimal binding features of Aza compounds with the heme-binding protein from Tannerella Forsythia for further consideration in drug discovery against the pathogen.

Keywords

Molecular docking, drug discovery, anti-microbial agents, Tannerella Forsythia, Aza compounds.

Citation

Sathiamurthy et al. Bioinformation 19(1): 53-56 (2023)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.