Title
Association of adiponectin levels with polycystic ovary syndrome among Indian women
Authors
Sudha Patil1, GK Veerabhadra Goud2,*, Rohini Nanjundappa, Shivashankar3, Senigala Kuruba Anusuya4 & Veluri Ganesh5
Affiliation
1Department of Obstetrics and Gynaecology, Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair - 744104, Andaman and Nicobar Islands, India; 2 Department of Biochemistry, Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair - 744104, Andaman and Nicobar Islands, India; 3Department of Obstetrics and Gynaecology, Akash Institute of Medical Sciences and Research Centre, Bangalore – 562110, Karnataka, India; 4Department of Obstetrics and Gynaecology, Akash Institute of Medical Sciences and Research Centre, Bangalore – 562110, Karnataka, India; 5Department of Biochemistry, Akash Institute of Medical Sciences and Research Centre, Bangalore – 562110, Karnataka, India; * Corresponding author
Sudha Patil- Email: sudhavpatil@gmail.com
Veerabhadra Goud GK Email: akashbiochemistry.edu.in@gmail.com
Rohini Nanjundappa Shivashankar- Email: dr.rohini.ns@gmail.com
SenigalaKurubaAnusuya- Email: parimalabv@yahoo.com
Veluri Ganesh - Email: ganeshbabu370@gmail.com
Article Type
Research Article
Date
Received September 2, 2022; Revised October 3, 2022; Accepted October 6, 2022, Published October 31, 2022
Abstract
Polycystic Ovary Syndrome (PCOS) is a hormonal condition where women reproductive hormones are out of endocrinal balance. Women with PCOS frequently exhibit obesity, which causes irregularities in the levels of adipocytes like adiponectin. It is hypothesized that the altered adiponectin levels also play a role in the endocrine and metabolic abnormalities seen in PCOS women. We aimed to study the association of adiponectin levels with PCOS women. This case control study included 60 PCOS women under 30 age, and BMI matched healthy controls were recruited. For all the subjects Biochemical and serum adiponectin were determined. The serum adiponectin shows significantly decreased in PCOS women when compared to healthy controls (P <0.001**). This levels were inversely associated with BMI and total cholesterol, triglycerides in women with PCOS (P<0.001**). The significantly decreased levels of serum adiponectin can be useful for diagnostic and prognostic tool for PCOS in women and its application can be used for the success of specific emerging treatment modalities where the follow up shows improvement of levels of adiponectin.
Keywords
Adiponectin, BMI and poly cystic ovary syndrome.
Citation
Patil et al. Bioinformation 18(10): 864-869 (2022)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
