Title
Metagenomic analysis of oral microbiota among oral cancer patients and tobacco chewers in Rajasthan, India
Authors
Mukesh Kumar Sharma*1, 2, Vivek Kumar Srivastav1, Chetan Kumar Joshi3, Mohan Kumar4 & K. Manohar Bhat5
Affiliation
1Department of Biotechnology, Maharaj Vinayak Global University, Jaipur Rajasthan, India; 2Department of Botany, Vishwa Bharti PG College, Sikar, Rajasthan India; 3Department of Zoology, Government Science College, Sikar, Rajasthan, India; 4Gyan Joyti College of Pharmacy and Nursing School, Hazaribagh, Jharkhand India; 5Department of Pedodontics and Preventive Dentistry, Jaipur Dental College, Jaipur, Rajasthan India; *Corresponding author
Mukesh Kumar Sharma – E-mail: mukeshsharma.dt@gmail.com
Vivek Kumar Srivastav - E-mail: viveksribiotech@gmail.com
Chetan Kumar Joshi - E-mail: cjoshisk@gmail.com
Mohan Kumar - E-mail: mohank087@gmail.com
K. Manohar Bhat - E-mail: kmanoharbhat@yahoo.co.in
Article Type
Research Article
Date
Received July 2, 2022; Revised September 30, 2022; Accepted September 30, 2022, Published September 30, 2022
Abstract
Data on the microbial composition among tobacco chewers and oral cancer patients in Rajasthan, India is of interest. NGS analysis from tobacco chewers and oral cancer comprised the most abundant and core microbial taxa in the oral cavity. It shows that highly pathogenic phylum consisting of 6% Fusobacteria and 9% Firmicutes are observed in oral cancer samples; whereas, 0.6% Treponema, 34% Firmicutes, 0.02% Mollicutes, and 4% Fusobacteria are seen in tobacco chewers. Thus, data shows that the most abundant and core microbial taxa are found in the oral cavity of tobacco chewers and oral cancer patients in Rajasthan, India.
Keywords
Tobacco chewers, oral cancer, meta-genomics, microorganism, oral
Citation
Sharma et al. Bioinformation 18(9): 757-763 (2022)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
