Title
Permafrost Immunity
Authors
Francesco Chiappelli1*& Jaden Penhaskashi2**
Affiliation
1Dental Group of Sherman Oaks, CA 91403 (www.oliviacajulisdds.com)
2West Valley Dental Implant Center, Encino, CA 91316 (minimallyinvasiveperio.com)
Chiappelli.research@gmail.com
Article Type
Editorial
Date
Received September 5, 2022; Revised September 30, 2022; Accepted September 30, 2022, Published September 30, 2022
Abstract
Thawing permafrost is a serious and worrisome threat to the environment, because it releases trapped heavy metals and greenhouse gasses. Thawing permafrost is also a health threat because, in addition to releasing these noxious gasses, thawing permafrost may free novel and undiscovered antibiotic-resistant bacteria, viruses, fungi and parasites among a plethora of dormant pathogens. Our immune system is ill-prepared to counter these challenges, and will require significant adaptation, or allostasis, which can be subsumed under the generic term of permafrost immunity. Since most of the most gravely threatening pathogens released by thawing permafrost are likely to penetrate the organism through the oral cavity, permafrost immunity may first be identified in the oral mucosa.
Keywords
Climate change, Global warming, Permafrost, Immune allostasis, Cellular immunity, Humoral immunity, Exhausted T cells, Cytokine Storm, Virus-Induced Autoimmunity, Oral health
Citation
Chiappelli & Penhaskashi, Bioinformation 18(9): 734-738 (2022)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
