Title

Molecular docking analysis of melamine with nuclear factor erythroid 2-related factor 2 and succinate dehydrogenase

Authors

Nitish Rai^1,*, Sheemona Chowdhary², Deepak Kumar², Rajasri Bhattacharyya^2,*& Dibyajyoti Banerjee^2,*

Affiliation

¹Department of Biotechnology, Mohanlal Sukhadia University, Udaipur, Rajasthan, India; ²Department of Experimental Medicine and Biotechnology, PGIMER, Chandigarh 160012, India; *Corresponding authors

Email

Nitish Rai - E-mail: nits6691@gmail.comand, nitish.rai@mlsu.ac.in

Rajasri Bhattacharyya - E-mail: bdr.rajasri@yahoo.in

Dibyajyoti Banerjee - E-mail: dibyajyoti5200@yahoo.co.in

Article Type

Research Article

Date

Received July 2, 2022; Revised August 31, 2022; Accepted August 31, 2022, Published August 31, 2022

Melamine consumption causes oxidative stress by an unknown mechanism. Therefore, it is of interest to analyze the interaction of melamine with two important proteins involved in oxidative stress biology namely, nuclear factor erythroid 2-related factor 2 and succinate dehydrogenase. The molecular docking data shows the melamine binding with these two proteins at critical residues. These interactions can be logically perceived for the causation of melamine induced oxidative stress.

Keywords

Citation

Rai et al. Bioinformation 18(8): 718-723 (2022)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.