Title

Molecular docking analysis of VEGF with compounds from tomato

Authors

Madhan Krishnan^1,*, Shyamaladevi Babu¹, Suni Ann Thomas², Jaya Senthilnathan Surulivel³, Kavitha Ayyanar⁴

Affiliation

¹Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, chengalpattu District, Tamilnadu, India; ²Department of Biochemistry, Al Azhar Medical College Thodupuzha, Kumaramangalam, Kerala, India; ³Department of General Medicine, Vels Medical College & Hospital, Vels Institute of Science Technology & Advance Studies (VISTAS), Chennai, Tamilnadu, India, ⁴Department of Biochemistry, Vels Medical College & Hospital, Vels Institute of Science Technology & Advance Studies (VISTAS), Chennai, Tamilnadu, India; *Corresponding author

Email

Madhan Krishnan - Email: kmadhan91@gmail.com

Shyamaladevi Babu - Email: syamdevi06@gmail.com

Suni Ann Thomas – Email: sunisarith@gmail.com

Jaya Senthilnathan S – Email: sjayasenthilnathan@gmail.com

Kavitha Ayyanar – Email: kaviaynam@gmail.com

Article Type

Research Article

Date

Received April 2, 2022; Revised May 31, 2022; Accepted May 31, 2022, Published May 31, 2022

Vascular endothelial growth factor (VEGF) is linked with Non-small cell lung carcinoma (NSCLC). Therefore it is of interest to document data on the molecular docking analysis of VEGF with compounds from tomato for consideration drug discovery. Data shows that compounds Kaempferol-3-O, Quercetin, Naringenin & Rutin show optimal binding.

Keywords

Molecular docking, VEGF, lung cancer, tomato

Citation

Krishnan et al. Bioinformation 18(5): 478-481 (2022)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.