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Title

Sequence to predicted structure and function for DHX8

Authors

Muhammed A Bakhrebah1, Majed S Nassar1,*, Fahad M Alhoshani1, Abdulkhaliq Munawir Alanazi2 & Saeed A Asiri3

 

Affiliation

1Life Science and Environment Research Institute, King Abdulaziz City for Science and Technology (KACST), P.O. Box 6086, Riyadh 11442, Kingdom of Saudi Arabia; 2Department of Respiratory Services, Ministry of National Guard Hospital and Health affairs (MNGHA), P.O. Box 22490, Riyadh, Kingdom of Saudi Arabia; 3Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Najran University; *Corresponding author

 

Email

Muhammed A Bakhrebah - E-mail: mbakhrbh@kacst.edu.sa
Majed S Nassar - E-mail: mnassar@kacst.edu.sa
Fahad M Alhoshani - E-mail:fhoshani@kacst.edu.sa
Abdulkhaliq Munawir Alanazi - E-mail:alanaziab33@ngha.med.sa
Saeed A Asiri - E-mail:saaasiri@nu.edu.sa

 

Article Type

Research Article

 

Date

Received March 1, 2022; Revised April 30, 2022; Accepted April 30, 2022, Published April 30, 2022

 

Abstract

DEAH-box helicase 8 (DHX8) is a protein coded by the DHX8 gene in humans. Available information on the sequence to structure to function for this protein is limited in the literature. Therefore, it is of interest to document insights gleaned from the sequence to structure to functional analysis of the DHX8 protein using known software tools such as SMART, Prosite, Pfam, PANTHER, and InterProScan. We also present the predicted preliminary structure data for the protein to glean structure based functional insights.

 

Keywords

DHX8, Pfam, Inter Pro Scan beta turn, α-helix, SMART, Prosite, PANTHER, Ramachandran plot, hydrophobicity and antigenic region

 

Citation

Bakhrebah et al. Bioinformation 18(4): 411-419 (2022)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.