Title
MUC4 and MMP7 in saliva and gingival crevicular fluid (GCF) in adolescents at West Bengal, India
Authors
Sayan Chattopadhyay1, Rachita Arora1, Amit Kishor2, Shivani Singh3, Abhijeet Alok4 & Mainak Mitra1
Affiliation
1Burdwan Dental College and Hospital, West Bengal, India; 2Primary Health Centre Baniyapur, Chapra, Bihar, India; 3Dr B R Ambedkar Institute of Dental Sciences and Hospital, Patna, Bihar, India; 4Primary Health Centre, Khaira, Jamui, Bihar, India; *Corresponding author
Sayan Chattopadhyay- E-mail:drsayan23@gmail.com
Rachita Arora- E-mail: rachita.arora1@gmail.com
Amit Kishore- E-mail: dramitkishor1@gmail.com
Shivani Singh- E-mail: drshivani37@gmail.com
Abhijeet Alok- E-mail: drabhijeetalok786@gmail.com
Mainak Mitra- E-mail: mmitra65@gmail.com
Article Type
Research Article
Date
Received January 3, 2022; Revised March 3, 2022; Accepted March 31, 2022, Published March 31, 2022
Abstract
Mucin 4 (MUC4) and matrix metalloproteinase 7 (MMP7) have been reported to be associated with chronic periodontitis as seen in gingival tissue biopsies. Therefore, it is of interest to estimate the levels of MUC4 and MMP7 in saliva and gingival crevicular fluid (GCF) samples of periodontitis in adolescents patients at West Bengal, India. MUC4 levels were significantly lower in saliva and GCF from periodontitis patients compared to healthy controls. However, MMP7 levels were found to be significantly higher in saliva and GCF from periodontitis patients. Thus, MUC4 and MMP7 are biomarkers for periodontitis diagnosis and towards further consideration.
Keywords
Gingival Crevicular Fluid (GCF), matrix metalloproteinase 7(MMP7), mucin 4(MUC4), periodontitis, saliva
Citation
Chattopadhyay et al. Bioinformation 18(3): 165-169 (2022)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
