Title

Atherogenic index of plasma, lipid accumulation and visceral adiposity in metabolic syndrome patients

Authors

M Sabarinathan¹, DS Deepak Rajan¹, N Ananthi*¹ & Madhan Krishnan²

Affiliation

¹Department of Biochemistry, Saveetha Medical College & Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam - 602015, Chennai, Tamilnadu, India; ²Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam-603103, Tamilnadu, India; *Corresponding author

Email

M Sabarinathan – E-mail:Labsabari1@gmail.com

DS Deepak Rajan – E-mail:Deepak_raj03@yahoo.com

N Ananthi - E-mail:n_ananthi@yahoo.com

Madhan Krishnan – E-mail:kmadhan91@gmail.com

Article Type

Research Article

Date

Received November 1, 2022; Revised November 29, 2022; Accepted November 30, 2022, Published November 30, 2022

Metabolic syndrome is a cluster of various clinical and biochemical abnormalities, needs early diagnosis and treatment to reduce morbidity and mortality. The present study is designed to compare Atherogenic Index of Plasma, Lipid Accumulation Product and Visceral Adiposity Index with metabolic syndrome components in patients with metabolic syndrome.  The study comprises of 150 metabolic syndrome patients and 150 age and sex matched healthy controls of both genders in the age group of 20 – 65 years. Atherogenic Index of Plasma, lipid accumulation and Visceral Adiposity Index product index were calculated for all participants. Pearson Correlation was used to compare atherogenic Index of plasma, lipid accumulation and Visceral Adiposity Index product between cases and controls. The receiver operating characteristic curve (ROC) was used to compare the area under the ROC curve (AUC) of Atherogenic Index of Plasma, lipid accumulation and Visceral Adiposity Index product with metabolic syndrome. The comparisons between the BMI, WC, Atherogenic Index of Plasma ,lipid accumulation and Visceral Adiposity Index product were significantly higher in metabolic syndrome cases (p <0.001).Although the entire index were independently associated with Mets, AIP showed the highest area under the curve (0.954, 95% CI 0.929 0.978,p value ≤0.0001) in identifying metabolic syndrome.

Keywords

Metabolic syndrome; Diabetes Mellitus; atherogenic index; adiposity index

Citation

Sabarinathan et al. Bioinformation 18(11): 1109-1113 (2022)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.