Title
A review on salivary constituents for diagnostics
Authors
Nishath Sayed Abdul1*, Sara Mohammed AlGhannam2, Atheer Abdulaziz Almughaiseeb3, Faisal Ahmed Bindawoad4, Sara Mohammed alduraibi5 & Mahesh Shenoy1
Affiliation
1Faculty of Oral and Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Riyadh Elm University, Riyadh, KSA; 2MOH, Prince Saud Bin Jalawi hospital, Alahsa, KSA; 3MOH, Al-Muzahmiyah general hospital, Riyadh, KSA; 4MOH, Thadiq general hospital, Riyadh, KSA; 5Dr. Sulaiman Alhabib, Altakhassusi Hospital, Riyadh, KSA; Communicated by Vini Mehta – E-mail: vinip.mehta@gmail.com
Nishath Sayed Abdul – E-mail: nishathsayed@riyadh.edu.sa
Sara Mohammed AlGhannam - E-mail: sara.m.alghanam@student.riyadh.edu.sa
Atheer Abdulaziz Almughaiseeb – E-mail: Atheer.a.almughaiseb@student.riyadh.edu.sa
Faisal Ahmed Bindawoad – E-mail: Faisal.a.dawoad@student.riyadh.edu.sa
Sara Mohammed – E-mail: Alduraibi-sara.m.alduraibi@student.riyadh.edu.sa
Mahesh Shenoy – E-mail: mahesh.shenoy@riyadh.edu.sa
Article Type
Research Article
Date
Received September 2, 2022; Revised October 3, 2022; Accepted October 6, 2022, Published October 31, 2022
Abstract
Salivary secretions possess a number of biomarkers beneficial for the diagnosis of a plethora of oral and other systemic disorders. Therefore, it is of interest to analyse and discuss the significance of saliva and its constituents as a valuable tool in aiding diagnostics in clinical settings by reviewing available literature and controlled trials. Using the PRISMA framework, a thorough review of research that were listed in the PubMed, Web of Science, and Cochrane library databases was performed which revealed 212 papers, 54 of which were thoroughly evaluated. Exclusion and inclusion criteria were used to choose studies that were applicable for the review. The selected studies reported a number of diseases that were diagnosed using salivary constituents in the same way as other methods of diagnosis, with a number of benefits. Thus, data shows that saliva is an excellent source for biomarkers which can be used for furthering medical diagnosis like other diagnostic procedures.
Keywords
Biomarker, diagnostics, saliva, salivary constituents, systemic diseases
Citation
Abdul et al. Bioinformation 18(10): 1021-1028 (2022)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
