Title

Myeloperoxidase and troponin T are linked with myocardial infarction among young Indians

Authors

Anoop Jaiswal¹, Beenu Doctor², Manish Kumar Verma³ & Amrita Vamne^1,*

Affiliation

¹Department of Biochemistry Index Medical College, Malwanchal University Indore, MP, India; ²Department of Biochemistry, Moti Lal Nehru Medical College, Prayagraj, UP, India; ³Department of Biochemistry, GSVM Medical College, Kanpur, UP, India; ^*Corresponding author

Email

Anoop Jaiswal – E-mail: biochemanoop11@gmail.com Beenu - E-mail:  dbeenu.santosh@gmail.com Manish Kumar Verma - E-mail: manishverma8919@gmail.com Amrita Vamne - E-mail: avamne@gmail.com

Article Type

Research Article

Date

Received November 21, 2021; Revised December 23, 2021; Accepted December 23, 2021, Published January 31, 2022

It is of interest to document the correlation of myeloperoxidase (MPO) and Troponin T (TnT) in young Indian patients with myocardial infarction using epidemiological data. A study with 220 (110 case and 110 control) participants with Acute Coronary Syndrome (both males and females) was completed. Patients were identified using a pre-designed PROFORMA at the OPD and IPD of the Medicine Department at the Index Medical College & Hospital, Malwanchal University and Moti Lal Nehru Medical College and Swaroop Rani Nehru Hospital in India. MPO and TnT were measured using the Sandwich ELISA (Sandwich Enzyme linked immunosorbent Assay) kit. TnT (pg/ml) (Mean ± SD) were high in the case group than control 134.7 ± 8.57 vs 96.6 ± 2.82; F = 145.9; t = 44.3; p < 0.01). Moreover, MPO was 3-fold high in case group than control (157±30.1 and 42.4±14.82, respectively). The differences was found statistically significant (p<0.001). This suggests a link between TnT and MPO among young Indian patients with myocardial infarction.

Keywords

Myocardial infarction, myeloperoxidase, Troponin T, Sandwich ELISA

Citation

Jaiswal et al. Bioinformation 18(1): 66-71 (2022)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.