Title
Views on high-fat diet linked insulin resistance
Authors
Priscilla Daniel1, Madhan Krishnan2,3, Monisha Prasad3, Shyamaladevi Babu3, & TM Vijayalakshm 1,*
Affiliation
1Department of Medical Biochemistry, Dr. A.L.M PG Institute of Basic Medical Sciences, University of Madras, Chennai, Tamil Nadu, India; 2Department of Biochemistry, Vels Medical college & Hospital, Vels Institute of Science Technology & Advance Studies (VISTAS), Chennai, Tamilnadu, India; 3Department of Biochemistry, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamilnadu, India. *Corresponding author
Priscilla Daniel - E-mail: danielpriscilla4@gmail.com Madhan Krishnan - E-mail: kmadhan91@gmail.com Monisha Prasad - E-mail: monishapandu3@gmail.com Shyamaladevi Babu - E-mail: shyamdevi06@gmail.com TM Vijayalakshmi – E-mail: proftmvijayalakshmi@gmail.com
Article Type
Views
Date
Received November 5, 2021; Revised December 16, 2021; Accepted December 16, 2021, Published January 31, 2022
Abstract
Insulin resistance is linked to impaired cell metabolism and survival in the peripheral tissues, as well as increased oxidative stress and activated inflammatory responses. Chronic High fat diet insulin resistant to exposure results in liver damage, impaired glucose homeostasis, hyperinsulinemia, late pancreatic-cell failure to generate insulin due to cell exhaustion, and subsequent hyperglycaemia, all of which are hallmarks of Type 2 Diabetes Mellitus (T2DM). Therefore, it is of intrest to document a short review on the impact of a high-fat diet with insulin resistance.
Keywords
Diabetes, high-fat diet, insulin resistance
Citation
Daniel et al. Bioinformation 18(1): 50-52 (2022)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
