Title

Insights from the molecular docking analysis of colistin with the PmrA protein model from Acinetobacter baumannii

Authors

Shalini Ganeshan¹, Mohammad Reza Shakibaie^2,3,*& Rajaguru Rajagopal⁴

Affiliation

¹Department of Biotechnology, Tips college of arts and science, Coimbatore, Tamil Nadu 641107, India; ²Department of Microbiology and Virology, Kerman University of Medical Sciences, Kerman, Iran; ³Environmental Health Engineering Research Center, Kerman University of Medical Science, Kerman, Iran; ⁴Research Scholar Department of Pharmaceutics, Mother Theresa Post Graduate and Research Institute of Health Sciences, Pondicherry-605006, India. ^*Corresponding author

Email

Shalini Ganeshan - E-mail: shalininov2015@gmail.com; Mohammad Reza Shakibaie - E-mail: mr_shakibaei@kmu.ac.ir; Rajaguru Rajagopal - E-mail: rajaguru94mrv@gmail.com

Article Type

Research Article

Date

Received October 27, 2021; Revised December 10, 2021; Accepted December 10, 2021, Published January 31, 2022

Acinetobacter baumannii (AB) is one of the most common causes of nosocomial infections. Therefore, it is of interest to design and develop drugs against Acinetobacter baumannii. A strain of AB showing MIC 32 μg/ml against colistin was isolated from a hospital environment in Iran. Hence, we document data to glean insights from the molecular docking analysis of colistin with the PmrA protein from this bacterium.

Keywords

Acinetobacter baumannii, protein modeling, model quality, molecular docking.

Citation

Ganeshan et al. Bioinformation 18(1): 41-49 (2022)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.