Title
Effect of Moringa oleifera leaves on hematological profile of fluorosis affected rats
Authors
Pravallika Pagadala1,*, MS Vinutha Shankar1, A Hemalatha2 & KN Shashidhar3
Affiliation
1Department of Physiology, Sri Devaraj Urs Academy of higher education & Research, Tamaka Kolar, Karnataka, 563103; 2Department of Pathology, Sri Devaraj Urs Academy of higher education & Research, Tamaka Kolar, Karnataka, 563103; 3Department of Biochemistry, Sri Devaraj Urs Academy of higher education & Research, Tamaka Kolar, Karnataka, 563103; *Corresponding author
Pravallika Pagadala, E-mail: pravallikapagadala5@gmail.com; Telephone - +91 9494208365, Fax- +01 08 152-243008. Orcid-0000-0001-6250-793X
Article Type
Research Article
Date
Received October 1, 2021; Revised November 14, 2021; Accepted November 14, 2021, Published January 31, 2022
Abstract
Fluorosis is a metabolic disease that is endemic in nearly 25 countries with India being one of the most affected. It primarily affects the bone and the teeth. Moringa oleifera (MO) leaves are known to reduce the effect of fluorosis on various tissues. Therefore, it is of interest to document the effect of Moringa oleifera leaves on the hematological profile of fluorosis affected rats. Twenty four Sprague Dawley rats were housed two per cage in a room with 12 hours light and 12 hours dark cycle. The rats were allowed to adjust to the laboratory environment for about one to two weeks before the beginning of the study. This study reveals that MO leaves is effective in reducing the plasma fluoride content. It also helps in improving the Hb % and RBC count in fluorosis affected rats. Data shows that Moringa olifera leaves powder is effective in reducing the plasma fluoride content. It also helps in improving the Hemoglobin percentage & Red Blood Cell count in fluorosis affected rats.
Keywords
Fluoride, anemia, intoxification, premature erythrocytes death, drinking water, Moringa Olifera
Citation
Pagadala et al. Bioinformation 18(1): 14-18 (2022)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
