Combined effect of furanone fluconazole and amphotericin B against biofilms formed from

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Title	Combined effect of furanone fluconazole and amphotericin B against biofilms formed from Cryptococcus neoformans
Authors	Kirishnamoorthy Meenakumari¹ & Giridharan Bupesh^1,2*
Affiliation	¹Research & Development Wing, Sree Balaji Medical College and Hospital (SBMCH), Bharath University, BIHER, Chrompet, Chennai-600044, Tamil Nadu, India; ²Department of Forest Science, Central University of Nagaland, Lumami, India
Email	*Corresponding author: Dr. Giridharan Bupesh - Email: bupeshgiri55@gmail.com
Article Type	Research Article
Date	Received January 15, 2021; Revised April 25, 2021; Accepted May 6, 2021, Published May 31, 2021
Abstract	It is of interest to document the combined effect of furanone fluconazole and amphotericin B against the biofilm formed by Cryptococcus neoformans. The MIC values of amphotericine B and Fluconazole were observed as 20μg/ml and 60μg/ml, respectively. The MIC for the Combination (Amphotericin B/ Fluconazole) was found to be at (15/20) μg/ml drug concentration. Thus, data shows the combined effect of furanone fluconazole and amphotericine B derivative against C. neoformans.
Keywords	Cryptococcus neoformans, fluconazole, amphotericin B, biofilm
Citation	Meenakumari & Bupesh, Bioinformation 17(5): 536-540 (2021)
Edited by	P Kangueane
ISSN	0973-2063
Publisher	Biomedical Informatics
License	This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.