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Known data on applied regenerative medicine in tendon healing



1Amit Lakhani, 1Ena Sharma*, 2Amit Kapila & 3Kavin Khatri



1Maharishi Markandeshwar College of Dental Sciences and Hospital Mullana, Ambala, Haryana, India; 2Consultant Fortis Hospital, Mohali, India; 3All India Institute of Medical Sciences, Bathinda, Punjab, India



Amit Lakhani - dramitlakhani@gmail.com (+91 9882382325); Ena Sharma - dr.sharma_ena@yahoo.co.in; (+91 8284855768); Amit Kapila - Email-amitkapila49@rediffmail.com (+91 9501085856); Kavin Khatri - Email: kavinkhatri84@gmail.com (+91 7837540662)


Article Type




Received February 28, 2021; Revised March 31, 2021; Accepted April 29, 2021, Published April 30, 2021



Tendons and ligaments are important structures in the musculoskeletal system. Ligaments connect various bones and provide stability in complex movements of joints in the knee. Tendon is made of dense connective tissue and transmits the force of contraction from muscle to bone. They are injured due to direct trauma in sports or roadside accidents. Tendon healing after repair is often poor due to the formation of fibro vascular scar tissues with low mechanical property. Regenerative techniques such as PRP (platelet-rich plasma), stem cells, scaffolds, gene therapy, cell sheets, and scaffolds help augment repair and regenerate tissue in this context. Therefore, it is of interest to document known data (repair process, tissue regeneration, mechanical strength, and clinical outcome) on applied regenerative medicine in tendon healing.



Tendon, ligament, ACL, PRP, stem cells, scaffolds, gene therapy



Lakhani et al. Bioinformation 17(4): 514-527 (2021)


Edited by

P Kangueane






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.