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Title

Molecular docking analysis of antimicrobial peptides with the CXCL1 protein target for colorectal cancer

 

Authors

Praveen Kumar Kumar* & Shanmughavel Piramanayagam

 

Affiliation

Computational Biology Lab, Department of Bioinformatics, Bharathiar University, Coimbatore - 641046, Tamil Nadu, India

 

Email

Praveen Kumar Kumar - sirajane@gmail.com; Dr. Shanmughavel Piramanayagam - shanmughavel@buc.edu.in

 

Article Type

Research Article

 

Date

Received February 28, 2021; Revised March 10, 2021; Accepted March 10, 2021, Published March 31, 2021

 

Abstract

Antimicrobial peptides (AMPs) play a prominent role in drug discovery due to the rapid increase in drug resistant infections. Hence, we report the molecular docking analysis of antimicrobial peptides MREEKKERKRD and MVQGAKRGGRLHRV with the target protein CXCL1 in the context of colorectal cancer for further consideration in drug discovery.

 

Keywords

Antimicrobial peptides; colorectal cancer; Peptide docking; Schrodinger.

 

Citation

Kumar & Piramanayagam, Bioinformation 17(3): 369-376 (2021)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.