Molecular docking analysis of vascular endothelial growth factor receptor with bioactive molecules from Piper longum as potential anti-cancer agents

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Title	Molecular docking analysis of vascular endothelial growth factor receptor with bioactive molecules from Piper longum as potential anti-cancer agents
Authors	Selvaraj Jayaraman^1,*, Vidhya Rekha Umapathy², Jayamathi Govindaraj³, Keerthidaa Govidaraj⁴
Affiliation	^1,*Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, India; ²Department of Public Health Dentistry, Sree Balaji Dental College and Hospital, Pallikaranai,Chennai-600 100, India; ³Department of Biochemistry, Sree Balaji Dental College and Hospital, Pallikaranai, Chennai-600 100, India; ⁴MGM Health Care, Nelson Manickam Road, Chennai- 600029, India;
Email	Dr. Selvaraj Jayaraman - Email: jselvaendo@gmail.com
Article Type	Research Article
Date	Received December 29, 2020; Revised January 15, 2020; Accepted January 26, 2020, Published January 31, 2021
Abstract	It is known that vascular endothelial growth factor receptor (VGFR) is linked with cancer. Therefore, it is of interest to document the molecular binding features of bioactive molecules from Piper longum as potential anti-cancer agents with VGFR2 for further consideration. Thus, we document the binding features of four compounds (sesamin, fargesin, longamide and piperlonguminine) with VGFR2 for further consideration in drug discovery.
Keywords	VEGFR; Piper longum; lung cancer; molecular docking
Citation	Selvaraj et al. Bioinformation 17(1): 223-228 (2021)
Edited by	P Kangueane
ISSN	0973-2063
Publisher	Biomedical Informatics
License	This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.