Molecular modeling of cornulin (CRNN) for docking with phytocompounds from Justicia adhatoda L.

HOME | PDF |

Title	Molecular modeling of cornulin (CRNN) for docking with phytocompounds from Justicia adhatoda L.
Authors	Jayaraman Selvaraj^1,*, Shazia Fathima JH², Venkatacalam Sivabalan³, Umapathy Vidhya Rekha⁴, Rajagopal Ponnulakshmi⁵, Veeraraghavan Vishnupriya¹, Malathi Kullappan⁶, Radhika Nalinakumari Sreekandan⁷, Surapaneni Krishna Mohan⁸, Periyasamy Vijayalakshmi⁸
Affiliation	¹Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, India; ²Department of Oral and Maxillofacial Pathology, Ragas Dental College and Hospitals, Chennai, India; ³Department of Biochemistry, KSR Institute of Dental Sciences and Research, Thiruchengodu-637215, India; ⁴Department of Public Health Dentistry, Sree Balaji Dental College and Hospital, Pallikaranai, Chennai-600 100, India; ⁵Central Research Laboratory, Meenakshi Academy of Higher Education and Research (Deemed to be University), Chennai-600 078, India; ⁶Department of Research, Panimalar Medical College Hospital & Research Institute, Varadharajapuram, Poonamallee, Chennai - 600 123, India; ⁷Department of Clinical Skills & Simulation, Panimalar Medical College Hospital & Research Institute, Varadharajapuram, Poonamallee, Chennai - 600 123, India;⁸Department of Biochemistry and Department of Clinical Skills & Simulation, Department of Research, Panimalar Medical College Hospital & Research Institute, Varadharajapuram, Poonamallee, Chennai - 600 123;
Email	Dr. Jayaraman Selvaraj - E-mail:jselvaendo@gmail.com
Article Type	Research Article
Date	Received December 29, 2020; Revised December 31, 2020; Accepted January 26, 2020, Published January 31, 2021
Abstract	Cornulin (CRNN) is linked with tumour progression. Therefore, it is of interest to document data on the molecular modeling of cornulin (CRNN) for docking with phytocompounds (Pyrazinamide, Anisotine, Vasicinone, Vasicoline) from Justicia adhatoda L. Thus, we document the optimal binding features of these compounds with the cornulin model for further consideration.
Keywords	Oral Squamous Cell Carcinoma, cornulin, molecular modeling, and molecular docking.
Citation	Selvaraj et al. Bioinformation 17(1): 200-205 (2021)
Edited by	P Kangueane
ISSN	0973-2063
Publisher	Biomedical Informatics
License	This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.