Identification of aspirin and diclofenac binding proteins in the red complex pathogens

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Title	Identification of aspirin and diclofenac binding proteins in the red complex pathogens
Authors	Geethika Babu¹, Veeraraghavan Vishnu Priya¹, Pothapur Keshaav Krishnaa¹, Rengasamy Gayathri¹ & Jayaseelan Vijayashree Priyadharsini²
Affiliation	¹Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai 600077, India; ²Biomedical Research Unit and Laboratory Animal Centre-Dental Research Cell, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai 600077, India;
Email	Veeraraghavan Vishnu Priya. Email id: vishnupriya@saveetha.com
Article Type	Research Article
Date	Received December 29, 2020; Revised December 31, 2020; Accepted January 26, 2020, Published January 31, 2021
Abstract	Red complex organisms are a group of organisms (Porphyromonas gingivalis ATCC 33277, Treponema denticola ATCC 35405, Tannerella forsythia ATCC 43037) that have been identified for the causation of periodontal diseases. Aspirin and diclofenac have been used as regular analgesics. Therefore, it is of interest to document the identification of aspirin and diclofenac binding proteins in the red complex pathogens using the STITCH v.5 pipeline. The virulence properties of these proteins were analyzed using VICMPred and VirulentPred software. Thus, we document 000 number of proteins having optimal binding features with the known analgesics.
Keywords	aspirin; aspirin;pathogens
Citation	Babu et al. Bioinformation 17(1): 192-199 (2021)
Edited by	P Kangueane
ISSN	0973-2063
Publisher	Biomedical Informatics
License	This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.