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Title

Protein targets in red complex pathogens for catechin

Authors

T. Cibikkarthik, A.S. Smiline Girija & J. Vijayashree Priyadharsini*

 

Affiliation

Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India; Corresponding author*

 

Email

J.Vijayashree Priyadharsini - Phone: +91 9941125984; E-mail: viji26priya@gmail.com T.Lakshmi – lakshmi@saveetha.com

 

Article Type

Research Article

 

Date

Received June 17, 2021; Revised September 27, 2021; Accepted September 27, 2021, Published December 31, 2021

 

Abstract

The development of antimicrobial drug resistance has encouraged scientists to develop alternate methods to combat infectious pathogens associated with dental diseases. Therefore, it is of interest to predict interactions for catechin (a plant derived compound) with protein targets in the red complex pathogens using computer aided network tools. However, in vitro and in vivo studies are warranted to confirm the antimicrobial effect of catechin (gallocatechin, epicatechin, epigallactocatechin (EGC) and gallolyl catechins) on the dental pathogens.

 

Keywords

Catechin, red complex pathogens, multi-drug transporters, efflux pumps.

 

Citation

Cibikkarthik et al. Bioinformation 17(12): 1105-1108 (2021)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.