Title

Molecular docking analysis of Enterotoxin I from Staphylococcus aureus with Nafcillin analogues

Authors

Jayaraman Selvaraj¹, Rajagopal Ponnulakshmi², Veeraraghavan Vishnupriya¹, Chandrasekar Kirubhanand^3*

Affiliation

¹Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, India; ²Central Research Laboratory, Meenakshi Academy of Higher Education and Research (Deemed to be University), West K. K. Nagar, Chennai-600 078, India; ³Department of Anatomy, All India Institute of Medical Sciences (AIIMS), Nagpur, India;

Email

Dr. Chandrasekar Kirubhanand - E.mail:kirubhanand@aiimsnagpur.edu.in; Corresponding author*

Article Type

Research Article

Date

Submitted on May 23, 2020; Revision August 15, 2020; Accepted August 15, 2020; Published October 31, 2020

Staphylococcal enterotoxins (SEs) are liked with food poisoning and other related infections. Nafcillin is an antibiotic used to treat the S. aureus. Therefore, it is of interest to study the molecular interactions of 25 nafcillin analogues with enterotoxin I using molecular docking analysis. The analysis shows optimal interaction features of Nafcillin analogues with Enterotoxin I from Staphylococcus aureus for further consideration.

Keywords

S. aureus, Nafcillin, enterotoxins I, molecular docking

Citation

Selvaraj et al. Bioinformation 16(10): 731-735 (2020)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.