Title

Molecular docking analysis of capsaicin with apoptotic proteins

Authors

Anitha Roy¹*, Arun Rasheed², Aneymol Varikalam Sleeba³, Ponnulakshmi Rajagopal⁴

Affiliation

¹Department of Pharmacology, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India; ²Department of Pharmaceutical Chemistry, Alshifa College of Pharmacy, Malappuram, Kerala; ³Department of Microbiology, St. Xavier’s College for Women, Aluva, Kerala-683101, India; ⁴Central Research Laboratory, Meenakshi Academy of Higher Education and Research (Deemed to be University), Chennai-600 078, India

Email

Dr. Anitha Roy - Email: anitharoy2015@gmail.com; *Corresponding author

Article Type

Research Article

Date

Submitted on May 23, 2020; Revision June 9, 2020; Accepted June 11, 2020; Published July 31, 2020

Oral cancer is linked with apoptotic proteins such as Bcl-xl, Bcl-2 & Mcl-1. Therefore it is of interest to document the molecular docking analysis of capsaicin (principle present in the Capsicum annum) with apoptotic proteins in this context. We report the molecular binding features of capsaicin with apoptotic proteins such as Bcl-xl, Bcl-2 & Mcl-1 for further consideration.

Keywords

Capsicum annum, oral cancer, molecular docking, ADME

Citation

Roy et al. Bioinformation 16(7): 555-560 (2020) 

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.