Title
Inhibitory studies of HepG2 and human immune cells using Solanum nigrum
Authors
Anbazhagan Ganesh Kumar1, Giridharan Bupesh3,5,*, Palanandi Sankarganesh 2,*, Sakthivel Vasanth3, Siddan Nandagopal4 and Baby Joseph5
Affiliation
1Department of Microbiology, Hindustan
College of Arts and Science, Padur, Chennai - 603 103, Tamil Nadu,
India; 2*& 5Center for Research and Consultancy, Hindustan Institute
of Technology and Science, Padur, Chennai-603103 Tamil Nadu, India;
3Research and Development
Wing, Sree Balaji Medical College and Hospital, Bharath Institute of
Higher Education & Research, Chromepet - 600 042, Tamil Nadu, India;
4Department of Botany, Government Arts College, Hosur 635001, Tamil
Nadu, India. 5Department of Forest Science, School of Science, Nagaland University (Central), Lumami, Zenheboto, Nagaland-798627,
India
*Corresponding authors: bupeshgiri55@gmail.com; bilisankar@gmail.com
Article Type
Research Article
Date
Received January 1, 2020; Revised June 3, 2020; Accepted June 5, 2020; Published July 31, 2020
Abstract
It is of interest to document the inhibitory studies of HepG2 and human immune cells using Solanum nigrum. We have assessed the effect of ethanolic extract from Solanum nigrum for antiproliferative on HepG2 and on human PBMC. Treatment with Solanum nigrum separates the cells that are estimated by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide measure. Results indicated improved cytotoxicity with expanding concentrations of extract.
Keywords
Inhibitory studies, HepG2, human immune cells, Solanum nigrum
Citation
Kumar et al. Bioinformation 16(7): 525-531 (2020)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
