Title

Molecular docking analysis of phytochemicals from ethanolic extract of Crescentia cujete with the auto inhibited parkin catalytic domain

Authors

P. Anitha¹,*, K. Praveen Kumar², P. Shanmughavel², TH. Nazeema³, G. Lalitha³

Affiliation

¹Department of Biochemistry, Rathnavel Subramaniam College of Arts and Science, Coimbatore, Tamilnadu; ²Department of Bioinformatics, Bharathiar University, Coimbatore, Tamilnadu; ³Michael Job College of Arts & Science for Women, Coimbatore, Tamilnadu;

Email

P Anitha E-mail – id: sai.anithabiochem@gmail.com ; Corresponding author :Anitha. P *Corresponding

Article Type

Research Article

Date

Received January 9 2020; Accepted February 20, 2020; Published February 29, 2020

The autoinhibited Parkin catalytic domain (PDB ID: 4BM9) receptor has been described to have a role in the ubiquitination of α-syn in Parkinson’s disease. Therefore, it is of interest to discuss the molecular docking analysis data of phytochemicals from ethanolic extract of Crescentia cujete with the auto inhibited Parkin catalytic domain. We report the docking features of the phytochemical named 1, 2-Ethanediamine, N-(2-aminoethyl) with the target protein for further consideration towards the design and development of anti-Parkinson
agents.

Keywords

Parkinson disease, Insilico docking, Crescentia cujete, autoinhibited Parkin catalytic domain.

Citation

Anitha et al. 16(2): 189-195 (2020)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.