Title
Association between the site of occurrence and pathological TNM staging in oral squamous cell carcinoma
Authors
R. Hannah* et al.
Affiliation
Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University 162, Poonamallee High Road, Chennai 600077
R. Hannah: E-mail - rgracedentist@gmail.com; *Corresponding author
Article Type
Research Article
Date
Received October 7, 2020; Revised October 27, 2020; Accepted October 27, 2020; Published December 31, 2020
Abstract
Oral cancer is a worldwide health problem. Risk factors for oral squamous cell carcinoma (OSCC) are tobacco, alcohol, betel nuts, viral infection and dietary habit. The site of occurence of the OSCC differs substantially between different people groups mainly because of variations in the prevalence of risk factors. The prognosis varies based on the site. pTNM is also one of the most useful tools for the prediction of prognosis. Therefore, it is of interest to correlate the pTNM staging with the site of occurrence of the lesion using 36 OSCC case reports. The results revealed 36.11% of the lesion occurred in buccal mucosa. Stage III pTNM was most prevalent in buccal mucosa and tongue and Stage IV pTNM in the retromolar trigone region by significant association with p value < 0.05. Thus, we report that lesions occurring in the Retromolar region, tongue and buccal mucosa need to be given special attention, as they are associated with early metastasis and poor prognosis. Early diagnosis and appropriate treatment protocol will improve the quality of life for the patients.
Keywords
oral squamous cell carcinoma; TNM staging; buccal mucosa; prognosis; tongue.
Citation
Hannah et al. Bioinformation 16(12): 1019-1025 (2020)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
