Title

Molecular docking analysis of a secondary metabolite with the glycoprotein receptors of HSV 1 and HSV 2

Authors

Natarajan Saran^1,2, Balaiyah Anandharaj², Giridharan Bupesh^1,3,*, Sakthivel Vasanth³, Joseph Pinto Jasmine Beulah³, Vellingiri Balachandar⁴

Affiliation

¹Department of Virology, King Institute of Preventive Medicine and Research, Chennai, India; ²Department of Microbiology, M.R. Government College, Mannargudi, India; ³Research & Development Wing, Sree Balaji Medical College and Hospital (SBMCH), Bharath University, BIHER, Chrompet, Chennai - 600044, Tamil Nadu, India; ⁴Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore Tamil Nadu, India

Email

Dr. G. Bupesh - E-mail: bupeshgiri55@gmail.com; Phone +91 8012405965; *Corresponding author

Article Type

Research Article

Date

Received October 18, 2019; Revised December 18, 2019; Accepted December 25, 2019; Published December 31, 2019

Herpes simplex viruses (HSV) are alpha herpes viruses, which causes life-threatening illness. Therefore, it is of interest to design and develop potential drugs to treat HSV infections. We show the optimal molecular docking properties of a secondary metabolite (3, 7, 11, 15 tetra methyl-2-2-hexadecen-‘1-ol) with the glycoprotein receptors of HSV1 and HSV 2 for further consideration.

Keywords

Herpes simplex virus 1 & 2, glycoprotein, PHYTOL, ADMET properties, drug likeliness

Citation

Saran et al. Bioinformation 15(12): 887-893 (2019)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.