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Title |
A comparative analysis of BCL-2 family |
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Authors |
Shouhartha Choudhury*
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Affiliation |
Department of Biotechnology, Assam University, Silchar-788011, Assam, India
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Shouhartha Choudhury – E-mail: shoutharthac@gmail.com; *Corresponding author
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Article Type |
Research Article
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Date |
Received December 12, 2018; Accepted January 7, 2019; Published April 15, 2019
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Abstract |
The BCL-2 family is conserved in evolution and shares a BCL-2 homology domain. It promotes and inhibits apoptosis. It is also known that apoptosis has a major role in effective cancer treatment. Therefore, it is of interest to document information related to the BCL-2 family of proteins for analysis by prediction tools. Hence, insights from a prediction based comparative functional analysis of 108 genes in this family are documented.
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Keywords |
BCL-2 family; pro-apoptotic; anti-apoptotic; and divergent genes.
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Citation |
Choudhury, Bioinformation 15(4): 299-306 (2019)
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Edited by |
P Kangueane
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ISSN |
0973-2063
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Publisher |
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License |
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
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