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Title

A comparative analysis of BCL-2 family

Authors

Shouhartha Choudhury*

 

Affiliation

Department of Biotechnology, Assam University, Silchar-788011, Assam, India

 

Email

Shouhartha Choudhury E-mail: shoutharthac@gmail.com; *Corresponding author

 

Article Type

Research Article

 

Date

Received December 12, 2018; Accepted January 7, 2019; Published April 15, 2019

 

Abstract

The BCL-2 family is conserved in evolution and shares a BCL-2 homology domain. It promotes and inhibits apoptosis. It is also known that apoptosis has a major role in effective cancer treatment. Therefore, it is of interest to document information related to the BCL-2 family of proteins for analysis by prediction tools. Hence, insights from a prediction based comparative functional analysis of 108 genes in this family are documented.

 

Keywords

BCL-2 family; pro-apoptotic; anti-apoptotic; and divergent genes.

 

Citation

Choudhury, Bioinformation 15(4): 299-306 (2019)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.