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Title

ASBAAC: Automated Salt-Bridge and AromaticAromatic Calculator

 

Authors

Chittran Roy & Saumen Datta*

 

Affiliation

Structural Biology and Bioinformatics Division, Council of Scientific and Industrial Research Indian Institute of Chemical Biology, 4 Raja SC Mullick Road, Jadavpur, Kolkata-700032, West Bengal, India;

 

Email

saumen_datta@iicb.res.in

 

Article Type

Software

 

Date

Received March 19, 2018; Revised April 5, 2018, Accepted April 5, 2018, Published April 30, 2018

 

Abstract

Biological systems are made of complex networks non-covalent interactions observed among protein-protein, protein-DNA, proteinlipid complexes using hydrogen-bonds, salt-bridges, aromatic-aromatic, van der Waals (vdW), hydrophobic-interactions and several others using distance criteria. Hence, large-scale data analysis is required to understand the principles of biological complex formation. Therefore, it is of interest to analyze non-covalent interaction namely, salt-bridge and aromatic-aromatic contacts in known and modeled protein complex structures. Here, we describe ASBAAC for automatic calculation of salt-bridges and aromatic-aromatic contacts in protein complexes. This software tool is fast, robust and user-friendly for large-scale analysis of inter-chain salt bridges and aromatic-aromatic contact in protein complexes.

 

Keywords

salt-bridges, aromatic-aromatic contacts, protein, program, software

 

Citation

Roy & Datta. Bioinformation 14(4): 164-166 (2018)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.