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Title

BlastXtract2: Improving early exploration of (meta) genomes

 

Authors

Heleen de Weerd1, Bernd E van der Veen2 & Marcus J Claesson3*

 

 

Affiliation

1Microbiology and Systems Biology, TNO, Zeist, The Netherlands; 2Genomics Core Facility, The Netherlands Cancer Institute, Amsterdam, The Netherlands; 3School of microbiology and alimentary pharmabiotic centre, university college cork, cork, Ireland

 

 

Email

m.claesson@ucc.ie; *Corresponding author

 

Article Type

Database

 

Date

Received March 21, 2015; Revised March 26, 2015; Accepted March 29, 2015; Published April 30, 2015

 

Abstract

To manage and intelligently mine the avalanche of genomic sequences intuitive and user-friendly graphical interfaces are required. Here we present BlastXtract2 which exclusively facilitates early exploration of un-annotated genomic and metagenomic sequences. Various formats of translated searches, including the commonly used BlastX, of multiple sequences against multiple protein databases can be uploaded to a relational database server, which can be accessed via a locally installed web-server. There, an intuitive GUI allows straightforward data-mining and enables quick detection of potential frameshifts and poorly sequenced or assembled regions, thereby contributing in making BlastXtract2 a unique and valuable tool for early exploration of (meta)genomic sequences. 

 

Availability

Source code, documentation and an online demo version are available at https://github.com/ ClaessonLab/ BlastXtract2.

 

Citation

Weerd et al.   Bioinformation 11(4): 173-175 (2015)
 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.