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Title

DB Dehydrogenase: an online integrated structural database on enzyme dehydrogenase

 

Authors

Suman Kumar Nandy1, Rajabrata Bhuyan1, 2 & Alpana Seal1, 2*

 

Affiliation

1Department of Biochemistry & Biophysics, University of Kalyani, Kalyani, Dt. - Nadia, West Bengal, India; 2BIF Centre, University of Kalyani, Kalyani, Dt - Nadia, West Bengal, India.

 

Email

aseal@klyuniv.ac.in; *Corresponding author

 

Article Type

Database

Date

Received September 26, 2012; Accepted October 04, 2012; Published October 13, 2012

 

Abstract

Dehydrogenase enzymes are almost inevitable for metabolic processes. Shortage or malfunctioning of dehydrogenases often leads to several acute diseases like cancers, retinal diseases, diabetes mellitus, Alzheimer, hepatitis B & C etc. With advancement in modern-day research, huge amount of sequential, structural and functional data are generated everyday and widens the gap between structural attributes and its functional understanding. DB Dehydrogenase is an effort to relate the functionalities of dehydrogenase with its structures. It is a completely web-based structural database, covering almost all dehydrogenases [~150 enzyme classes, ~1200 entries from ~160 organisms] whose structures are known. It is created by extracting and integrating various online resources to provide the true and reliable data and implemented by MySQL relational database through user friendly web interfaces using CGI Perl. Flexible search options are there for data extraction and exploration. To summarize, sequence, structure, function of all dehydrogenases in one place along with the necessary option of cross-referencing; this database will be utile for researchers to carry out further work in this field.

 

Availability

http://www.bifku.in/DBD/

 

Keywords

Dehydrogenase, Database, Oxidoreductase, Structure, Annotation

 

Citation

Nandy et al. Bioinformation 8(20): 1000-1002 (2012)
 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.