Title |
RDNAnalyzer: A tool for DNA secondary structure prediction and sequence analysis
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Authors |
Muhammad Afzal1, 2, Ahmad Ali Shahid1, Abida Shehzadi1*, Shahid Nadeem2 & Tayyab Husnain1 |
Affiliation |
1Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan; 2Department of Bioinformatics and Biotechnology, GC University, Faisalabad, Pakistan.
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|
abida_ravian@hotmail.com; *Corresponding author
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Article Type |
Software |
Date |
Received June 26, 2012; Accepted July 05, 2012; Published July 21, 2012
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Abstract |
RDNAnalyzer is an innovative computer based tool designed for DNA secondary structure prediction and sequence analysis. It can randomly generate the DNA sequence or user can upload the sequences of their own interest in RAW format. It uses and extends the Nussinov dynamic programming algorithm and has various application for the sequence analysis. It predicts the DNA secondary structure and base pairings. It also provides the tools for routinely performed sequence analysis by the biological scientists such as DNA replication, reverse compliment generation, transcription, translation, sequence specific information as total number of nucleotide bases, ATGC base contents along with their respective percentages and sequence cleaner. RDNAnalyzer is a unique tool developed in Microsoft Visual Studio 2008 using Microsoft Visual C# and Windows Presentation Foundation and provides user friendly environment for sequence analysis. It is freely available.
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Availability |
http://www.cemb.edu.pk/sw.html
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Keywords |
Sequence analysis, DNA, nucleotides, Nussinov algorithm, C# language
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Citation |
Afzal et al.
Bioinformation 8(14): 687-690 (2012) |
Edited by |
P Kangueane
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ISSN |
0973-2063
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Publisher |
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License |
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License. |