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Title

BiodEnz:A database of biodegrading enzymes

 

Authors

Shobana Sugumaran1*, Berlathangam2

 

Affiliation

1SRM University, School of Bio-engineering, Department of Bioinformatics, SRM Nagar, Kattankulathur-603203, Kancheepuram District, Tamil Nadu; 2SRM University, School of Bio-engineering, Department of Biotechnology, SRM Nagar, Kattankulathur-603203, Kancheepuram District, Tamil Nadu

 

Email

ksemaa@gmail.com; *Corresponding author

 

Article Type

Database

 

Date

Received May 01, 2011; Accepted Jully 05, 2011; Published January 06, 2012

 

Abstract

Azo dyes, which re characterized by azo bonds, are a predominant class of colorants used in tattooing, cosmetics, foods, textile and consumer products. Laccases (EC 1.10.3.2), lignin peroxidases (EC 1.11.1.14) , Azo reductases (EC 1.7.1.6) of different micro organisms are mainly useful for the development of biodegradation systems as they catalyse reductive cleavage of azo groups (-N=N-) . Laccases have very broad substrate specificity with respect to the electron donor and is capable of oxidizing phenols and aromatic amines. Azoreductase belongs to the family of oxidoreductases, acting on other nitrogenous compounds as donors with NAD+ or NADP+ as acceptor. Lignin peroxidase enzymes are highly non-specific and are well reported to decolourize various dyes We have developed BiodEnz database by collecting information like strains that produce particular enzymes, azo dyes that are degraded , substrate specificity, molecular weight, the optimum temperature and pH, sequence data of the above enzymes ,as the most effective inoculants used for bioremediation are able to degrade dyes over a broad concentration range, tolerate a range of environmental conditions of temperature, pH, and activity of the enzymes. The database can be searched by using a user friendly web interface.

 

Keywords

Azodyes, azolinkages, bioaugmentation, biodegradation, enzyme specificity

 

Citation

Sugumar & Berlathangam, Bioinformation 8(1): 040-042 (2012)
 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.