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Title

On experiences of i2b2 (Informatics for integrating biology and the bedside) database with Japanese clinical patients data
 

Authors

Takako Takai-Igarashi1*, Ryo Akasaka2, Kenji Suzuki2, Takahisa Furukawa2, Makiko Yoshida2, Keisuke Inoue2, Tomohisa Maruyama2, Toshimasa Maejima2, Masahiro Bando2, Masakazu Takasaki2, Miki Sakota2, Maki Eguchi2, Akihiko Konagaya3, Hiroya Matsuura3, Toyotaro Suzumura3, Hiroshi Tanaka1
 

Affiliation

1Graduate School of Biomedical Science, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8510 Japan; 2Educational Program for Bio-Medical OMICS Information, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8510 Japan; 3Interdsciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, 226-8503 Japan 

Email

takai.com@mri.tmd.ac.jp; *Corresponding author

Phone

+81-3-5803-4763

 

Fax

+81-3-5803-0247

 

Article Type

Database

 

Date

Received March 04, 2011; Accepted March 07, 2011; Published March 26, 2011

 

Abstract

Informatics for Integrating Biology and the Bedside (i2b2) is a database system to facilitate sharing and reuse of clinical patientsí data collected in individual hospitals. The i2b2 provides an ontology based object-oriented database system with highly simple and flexible database schema which enables us to integrate clinical patientsí data from different laboratories and different hospitals. 392 patientsí data including carcinoma and non-carcinoma specimens from cancer patients are transported from the Integrated Clinical Omics Database (iCOD) to the i2b2 database for a feasibility study to check applicability of i2b2 ontology and database schema on Japanese clinical patientsí data. No modification is required for the i2b2 data model to deal with Japanese characters. Some modification of ontology is required to integrate biomedical information extracted from the cancer patientsí data. We believe that the i2b2 system will be practical infrastructure to integrate Japanese clinical databases if appropriate disease ontology for Japanese patients is provided.  

Availability

http://bio-omix.tmd.ac.jp/disease/i2b2/

 

Citation

Takai - Igarashi et al. Bioinformation 6(2): 86-90 (2011)

Edited by

TW Tan

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.