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Title

 

 

 

 

TeCK Database: A comprehensive collection of telomeric and centromeric sequences with their associated proteins 

 

Authors

Ragul Gowthaman*, Saranya Krishnamoorthy, Renuka Devi Nandakumar, Vishalini Ayyarappan

 

Affiliation

Department of Bioinformatics, School of Chemical and Biotechnology, Shanmugha Arts Science Technology & Research Academy (SASTRA) SASTRA University, Thanjavur, India

Email

g.ragul@gmail.com; * Corresponding author

Article Type

Web Database

 

Date

received May 11, 2007; revised July 28, 2007; accepted October 12, 2007; published online October 15, 2007

 

Abstract

Telomeres and centromere are two essential features of all eukaryotic chromosomes. Each provides unique function that is absolutely necessary for the stability of chromosomes. We developed a comprehensive database named TeCK, which covers a gamut of sequence and other related information about telomeric patterns, telomere repeat sequences, centromere sequences and centromeric patterns present in chromosomes. It also contains information about telomerase ribo-nucleoprotein complexes, centromere binding protein and centromere DNA-binding protein complexes. The database also includes a collection of all kinetochore-associated proteins including inner, outer and central kinetochore proteins.  The database can be searched using a user-friendly web interface.

 

Availability

http://www.bioinfosastra.com/services/teck/index.html

 

Keywords

 

telomere; centromere; chromosome; kinetochore proteins

Citation

Gowthaman et al., Bioinformation 2(2): 73-75 (2007)

Edited by

P. Kangueane

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.