Title

Hypo, hype and ’hyp’ human proteins

Authors

Prashanth Suravajhala

Affiliation

Institute for Science, Systems and Models, Roskilde University, DK 4000 Roskilde, Denmark

Email

prash@ruc.dk;* Corresponding author

Article Type

Views & Challenges

Date

received April 11, 2007; revised June 12, 2007; accepted July 05, 2007; published online July 10, 2007

Abstract

Genes with unknown function are called orphan genes while their transcripts and peptides are called hypothetical proteins. There are many genes and their associated proteins that remain uncharacterized in the human genome. A database of human hypothetical proteins with ascribed functions could be helpful for biologists to search for potential proteins of interest. In recent years, the rapid completion of genome sequences has created essential information to link genes to gene products. In order to better explain functions for un-annotated proteins we designed BioinformaTRICKS (an open source) and used it to develop a database called HYPO. The database is available for free at http://pc-dugong.ruc.dk:8080.

Keywords

hypothetical proteins; mining; database; networks

Citation

Suravajhala, Bioinformation 2(1): 31-33 (2007)

Edited by

P. Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.